Special Session 94: Computational and Mathematical Approaches to Understanding Complex Biological Systems

Threshold dynamics of an age-structured HIV model

Yuan Yuan
Memorial University of Newfoundland, St. John`s
Canada
Co-Author(s):    Hu, Dandan
Abstract:
We incorporate both virus-to-cell and cell-to-cell transmissions into an age-structured withinhost virus infec8on model with cytotoxic T lymphocyte immune response. We have established local stability of feasible steady states, by analyzing the characteristic equations, and discussed the global threshold dynamics by using Lyapunov functionals and LaSalle invariance principle.