| Abstract: |
| Dengue is a viral infection transmitted by mosquitoes that primarily occurs in tropical and subtropical regions worldwide. The use of Wolbachia bacterium to infect mosquitoes has been shown to disrupt the cycle of dengue transmission, reducing the level of the virus in mosquitoes and shortening their lifespan. Studies have demonstrated that infecting and releasing Wolbachia-infected mosquitoes through Transinfection can spread the bacterium to local mosquito populations and mitigate the disease`s impact. To investigate the potential for Wolbachia to reduce Dengue virus transmission in humans, a mathematical model was developed that considers local temperature data, which affects mosquito reproduction and growth. The model simulation suggests that the outbreak of Dengue fever can be mitigated by releasing a small number of Wolbachia-infected mosquitoes at the appropriate time. |
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