Special Session 66: Dynamics of biological materials across scales

Kinetic Monte Carlo Simulations of Multicellular Aggregate Self-Assembly in Biofabrication

Yi Sun
University of South Carolina
USA
Co-Author(s):    Xiaofeng Yang, Qi Wang
Abstract:
We present a 3D lattice model to study self-assembly of multicellular aggregates by using kinetic Monte Carlo (KMC) simulations. This model is developed to describe and predict the time evolution of postprinting structure formation during tissue or organ maturation in a novel biofabrication technology--bioprinting. Here we simulate the self-assembly and the cell sorting processes within the aggregates of different geometries, which can involve a large number of cells of multiple types.