| Abstract: |
| Chromosomes are not distributed randomly in the nucleus. Understanding the spatial dynamics of the genome is a crucial step in characterizing how DNA adopts and transitions between different functional states over the course of the cell cycle, facilitating vital functions such as gene expression, DNA replication, recombination, and repair.
In this talk we explore the organizational principles of the yeast genome using models derived from polymer physics and Brownian dynamics simulations.
This work is a collaboration with Kerry Bloom`s lab in the biology department at UNC-CH and Greg Forest`s group in the math department at UNC-CH. |
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