2023 Wilmington NC USA


  Contributed Session 3:  Modeling, Math Biology and Math Finance
Analysis of neuronal oscillations of fractional-order Morris-Lecar model
Tahmineh Azizi
University of Wisconsin-Madison
USA
  Co-Author(s):    
  Abstract:
 

Fractional calculus as a new approach for modeling has been used widely to study the nonlinear behavior of physical and biological systems with some degrees of fractionality or fractality using differential and
integral operators with non integer orders. In this paper, to explore different dynamical classes of the Morris Lecar neuronal model with chloride channel, we extend its integer order domain into a new fractional order space using fractional calculus. The nonstandard finite difference (NSFD) method following the Grunwald Letnikov discretization may be applied to discretize the model and obtain the fractional order form. Fractional derivative order has been used as a new control parameter to extract variety of neuronal firing patterns that happen in real world application but the integer order operator may not be able to reveal them. To find the impact of chloride channel on dynamical behaviors of this neuronal model, the phase portrait and time series analysis have been performed for different fractional orders and input currents. Depending on different values for fractional derivative, the fractional order Morris Lecar model with a chloride channel reproduces quiescent, spiking and bursting activities the same as the fractional order Morris Lecar model without a chloride channel. We numerically discover the occurrence of hopf bifurcation, and homoclinic bifurcation for these two models.