| Abstract: |
| In medical science the use of nanofluids are emerging trend. In this study we isolated Candida (Yeast) that causes many infections in humans. It is the main cause of biofilm formation on implants specially catheters etc that may contribute in the Fungal resistance to antifungals. In this study, samples were collected and new nanostratigies applied to overcome the drugs resistance.. The capacity of biofilm production by Candida species was very high. Almost all species produced biofilm. The strongest biofilms were produced by Candida tropicalis. . We performed antimicrobial sensitivity assay by using different antifungals drugs. Moreover, nanoscale strategies were also applied; Gold nanoparticles were synthesized with drug conjugates and these were tested against these fungal isolates. Gold nanoparticles and drug-Gold nanoparticles conjugates were anti-Candida agents in our study. Gold nanoparticles and drug-conjugated Gold nanoparticles inhibited biofilm formation significantly. |
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