Special Session 16: 

Transitions in a genetic transcriptional regulatory system under L\`{e}vy motion

Yayun Zheng
Huazhong University of Science and Technology
Peoples Rep of China
Co-Author(s):    
Abstract:
Based on a stochastic differential equation model for a single genetic regulatory system, we examine the dynamical effects of noisy fluctuations, arising in the synthesis reaction, on the evolution of the transcription factor activator in terms of its concentration. The fluctuations are modeled by Brownian motion and $\alpha$-stable Levy motion. Two deterministic quantities, the mean first exit time (MFET) and the first escape probability (FEP), are used to analyse the transitions from the low to high concentration states. A new geometric concept is introduced to quantify the basin stability of the low concentration region, characterised by the escaping behaviour.