| Abstract: |
| Breast cancer is the second most commonly diagnosed cancer in women worldwide. MCF-7 cell line is an extensively studied human breast cancer cell line. This cell line expresses estrogen receptors, and the growth of MCF-7 cells is hormone dependent. In this study, I will present a mathematical model governing MCF-7 cell growth and interaction among tumor cells, estradiol, and immune cells. Experimental data will be used for the development of functional forms and estimation of parameter values. Breast tumor formation and growth will then be studied.
Keywords: Mathematical modelling, cancer, bifurcation analysis, numerical simulation, |
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