| Name |
Claudio Mirasso |
| Country |
Spain |
| Email |
claudio@ifisc.uib-csic.es |
| Co-Author(s) |
Fernanda S. Matias, Leonardo L. Gollo, Pedro V. Carelli, Mauro Copelli, and Claudio R. Mirasso |
| Submit Time |
2014-04-01 02:50:35 |
Session |
Special Session 77: Theoretical, technical, and experimental challenges in closed-loop approaches in biology
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| Contents |
| When the connectivity between two brain regions is such that one them (the sender) strongly influences the other (the receiver), a positive phase lag is often expected. The assumption is that the time difference implicit in the relative phase reflects the transmission time of neuronal activity. However, experiments performed in monkeys engaged in processing a cognitive
task, a dominant directional influence from one area of sensorimotor cortex to another may be accompanied by either a negative or a positive time delay. Here we present a model of two brain regions, coupled with a well-defined directional influence, that displays similar features to those observed in the experimental data. By reproducing experimental delay times and coherence spectra, our results provide a theoretical basis for the underlying mechanisms of the observed dynamics, and suggest that inhibitory neurons might play a crucial role in the response time of neuronal populations.. |
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