Display Abstract

Title Mathematical Concepts in Pharmacokinetics and Pharmacodynamics

Name Johannes Schropp
Country Germany
Email johannes.schropp@uni-konstanz.de
Co-Author(s) Gilbert Koch
Submit Time 2014-02-28 04:41:58
Session
Special Session 6: Random dynamical systems in the life sciences
Contents
The objective of this talk is to present and to analyze fundamental concepts of pharmacokinetic (PK) and pharmacodynamic (PD) modeling from a mathematical point of view. It turns out that any PKPD model is a nonautonomous dynamical system driven by the drug concentration. Moreover, we state convergence results between two widely used models, namely, transit compartments and lifespan models.