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Cancer appears as a result of genetic and epigenetic events and is characterized by a proliferation of uncontrolled tissue cells to form a tumor mass. Tumor cells carry specific antigens recognized by the immune system that triggers an anti-tumor immune response and then cancer competes with the immune system. Although chemotherapy and immunotherapy have different mechanisms of action and toxicities, These two therapies can be combined. The combination therapy is a treatment that uses more than one anticancer drug to prevent resistance mechanisms of cancer cells and to increase treatment effectiveness. In this ODE 's model , we will consider two cell populations: a population of tumor cells and a population of cytotoxic effector cells , namely NK cells or CD8 + T cells.
Our goal will be to highlight the effect of a combination therapy.. |
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