| Abstract: |
| The focus of this study is to investigate the effects of different stress levels on cognitive outcomes. Emerging evidence has shown that stress-induced release of glucocorticoids acts on glutamate neurotransmission and consequently influences the functionality of cognitive processing. By incorporating the Hypothalamic-pituitary-adrenal (HPA) axis and neuron models, we study the plasticity regulation outcomes based on two types of stress: stress with regular object and stress object with PTSD. The results can help to understand the dynamical mechanism between the glucocorticoids releasing and the neuron plasticity changes due to different stress levels. |
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