| Abstract: |
| Aspiration thrombectomy has emerged as a critical intervention for ischemic stroke caused by large vessel occlusions, wherein a catheter is navigated to the occlusion site and suction is applied to restore cerebral blood flow. To facilitate efficient computational analysis of this procedure, we present a new one-dimensional fluid-structure interaction model that captures the essential hemodynamics while decreasing computational cost compared over three-dimensional simulations. The model includes detailed constitutive modeling of the catheter material properties and accounts for viscoelastic effects in the blood flow through a Voigt-Kelvin pressure formulation. To address the resulting coupled hyperbolic system, we construct problem-suited nodal solvers based on hyperbolic relaxation, which are integrated into a splitting approach to derive an efficient numerical scheme capable of simulating realistic therapy scenarios. We validate the proposed 1D model against experimental measurements from an in-vitro physical model and demonstrate good agreement with fully resolved 3D CFD simulations, establishing the reduced model`s potential for clinical translation in thrombectomy planning. |
|