Mathematical Modeling and Quantitative System Pharmacology
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Organizer(s): |
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Affiliation:
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Christopher Denaro
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Rutgers University - Camden
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USA
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Benedetto Piccoli
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Rutgers University - Camden
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USA
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Abstract:
| | This special session will focus on the growing field of quantitative systems pharmacology. In recent years, clinical trials addressing neurodegenerative and other rare diseases have faced complications with disease pathophysiology and drug-target engagement. The field of quantitative systems pharmacology aims to address these issues in a data-driven, mechanistic way by using mathematical models to estimate human-disease interaction. QSP model development strikes a difficult balance between complexity and simplicity, as model priors must be informed by clinical or experimental data. This special session serves to bring together modelers from mathematical, systems biological, and regulatory background to address common challenges and identify best practices when developing quantitative systems pharmacology models. |
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List of approved abstract |
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