| Abstract: |
| Dengue is a viral infectious disease, mainly transmitted by Aedes aegypti and Aedes albopictus. It causes high morbidity and mortality in tropical and subtropical regions. Wolbachia is considered as a biological weapon against dengue virus because mosquitoes infected with Wolbachia is less capable of transmitting dengue virus. In this talk, I present modelling the mitigation strategies of dengue virus transmission using Wolbachia. I analyzed the stability of the disease free equilibrium and endemic equilibrium. Sensitivity analysis determined how sensitive the basic reproduction number, and the population at disease free equilibrium and endemic equilibrium respond to the change of the parameters. Numerical simulations compared different release strategies. Our model and analysis provided guidance for releasing Wolbachia-infected mosquitoes. |
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